What Is Sinuva
Sinuva (Mometasone) is a steroid. It stops the body from releasing chemicals that lead to inflammation.
Adults and children who are at least 12 years old can avoid seasonal allergy symptoms by using Sinuva (for the nose). Nasal polyps are also treated with Sinuva, although only in adults. There are additional uses for mometasone that are not covered in this pharmaceutical guide.
The SINUVA Sinus Implant is a self-expanding, bioabsorbable, drug eluting implant provided with a crimper and a single-use delivery system. SINUVA Sinus Implant is comprised of poly(L-lactide-co-glycolide) and poly(L-lactide-co-⃞-caprolactone) coated with mometasone furoate embedded in a bioabsorbable polymer matrix containing poly(DL-lactide-co-glycolide) and polyethylene glycol (inactive ingredients) which provides for gradual release of the drug. The SINUVA Sinus Implant is packaged in a tray, which is then sealed in a foil pouch and placed in the product carton. The SINUVA Sinus Implant is provided sterile.
Mometasone furoate, the active component of the SINUVA Sinus Implant, is a corticosteroid with the chemical name 9,21-dichloro-11(⃞),17-dihydroxy-16(⃞)-methylpregna-1,4-diene-3,20- dione 17 (2-furoate). Mometasone furoate is a white powder with an empirical formula of C27H30Cl2O6, and molecular weight of 521.44 Daltons.
Side Effects Of Sinuva
Sinuva may cause serious side effects. Call your doctor at once if you have:
- Severe bleeding or increased drainage from your nose
- Nose pain or discomfort, headache
- White patches or sores in the nose that won’t heal
- Wheezing, trouble breathing
- Vision problems
- Irritation or a choking feeling in the back of your throat (may be signs that the implant has moved inside your nose); or
- Ear pain or full feeling, trouble hearing, drainage from the ear.
Steroid medicine can affect growth in children. Tell your doctor if your child is not growing at a normal rate while using Sinuva.
Although the risk of serious side effects is low when mometasone is used in the nose, side effects can occur if the medicine is absorbed into your bloodstream. Tell your doctor if you have possible signs of long-term steroid use:
- Weight gain (especially in your face or your upper back and torso)
- Slow wound healing, thinning skin, increased body hair
- Irregular menstrual periods, changes in sexual function; or
- Muscle weakness, tired feeling, depression, anxiety, or feeling irritable.
Common side effects of Sinuva may include:
- Nosebleeds
- Headache
- Stuffy nose, sore throat, cough; or
- Flu-like symptoms.
Prior To Taking This Medication
You should not use Sinuva if you are allergic to mometasone.
Tell your doctor if you have ever had:
- An active or chronic infection
- Glaucoma or cataracts
- Herpes simplex virus of your eyes
- Tuberculosis or any other infection or illness
- Sores or ulcers inside your nose
- Nasal surgery or injury to your nose; or
- If you are not feeling well or have symptoms that you do not understand.
If you are nursing or pregnant, let your doctor know.
Mometasone nasal spray is not authorized to treat nasal polyps in those under the age of eighteen or to prevent allergy symptoms in those under the age of twelve. Anyone under the age of eighteen is not permitted to utilize a mometasone nasal implant.
How Should Sinuva Be Used
Read any drug guidelines and instruction sheets, and adhere to all instructions on your prescription label. Take the medication precisely as prescribed.
Avoid taking it orally. You should only use Sinuva in your nose.
Two to four weeks before to the onset of allergy season, your doctor might advise you to begin taking Sinuva.
Any Instructions for Use that come with your medication should be carefully read and followed. If you don’t understand these directions, ask your doctor or pharmacist.
Before using the nasal spray, give it a good shake. Spray the medication into the air until a fine mist forms to prime the nasal spray pump before using it for the first time. Prime the nasal spray by misting the medication into the air until a fine mist forms if it hasn’t been used for more than a week.
Your symptoms might not get better for up to two weeks. If your symptoms do not get better, continue taking the medication as prescribed and let your doctor know.
Mometasone can also be administered as a tiny implant placed in your nose to treat nasal polyps. In a medical environment, this implant is administered. Using a specialized instrument made to precisely put the implant inside the nose, a medical professional will insert the device.
Over the course of ninety days, the implant will gradually release mometasone into your nose. To keep the implant moist, you might also need to utilize saline nasal sprays or rinses. While your implant is in place, adhere to all care recommendations.
Sneezing or blowing your nose may cause the implant to come out as it eventually softens. Your doctor may remove the implant at any moment.
To ensure that the medication or the implant is not damaging your sinuses or nose, you will require regular medical examinations.
Mometasone nasal spray should be kept at room temperature, upright, and away from heat and moisture. Even if there is still medication in the bottle, discard it once you have taken 120 sprays.
What Happens If I Fail To Take A Dose
Take the medication as soon as you can, but if your next dose is close due, skip the missed one. Avoid taking two doses at once.
What Is The Outcome Of Overdosing
Call the Poison Help line or seek emergency medical treatment.
Life-threatening effects are not anticipated from a Sinuva overdose. High dosages taken over an extended period of time may cause thinning skin, easy bruising, changes in body fat (particularly in the face, neck, back, and waist), increased facial hair or acne, menstruation issues, impotence, or a loss of desire in sex.
What Should I Avoid While Using Sinuva
If Sinuva gets in your eyes, rinse with water.
Stay away from sick or infected persons. If you have been exposed to measles or chickenpox, call your doctor for preventive care. For those who use steroid medications, these diseases may be deadly or extremely dangerous.
How Will Sinuva Be Affected By Other Drugs
Certain drugs should not always be taken together. Certain prescriptions have the potential to alter the blood levels of other medications you take, which could worsen side effects or reduce their efficacy.
Inform your physician about all additional medications you use, particularly:
- An antibiotic
- Antifungal medicine
- An antidepressant; or
- Antiviral medicine to treat HIV/AIDS.
This is not an exhaustive list. Sinuva may also be impacted by vitamins, herbal supplements, and prescription and over-the-counter medications. This list does not include every potential drug interaction.
Contraindication
Certain drugs or supplements may interfere with Sinuva (mometasone). Any additional medications or supplements you are currently taking, including vitamins, dietary or herbal supplements, and prescription and over-the-counter medications, should always be disclosed to your doctor and pharmacist. Not all potential medication interactions with Sinuva (mometasone) are included in the list below. Please be aware that the list below only includes each medication’s generic name.
While there are some medications that should never be taken together, there are other situations in which two separate medications can be used together despite the possibility of an interaction. Your doctor might wish to adjust the dosage in these situations, or other safety measures might be required. It is especially crucial to let your healthcare provider know if you are taking any of the following medications while taking this medication. The following interactions are not necessarily all-inclusive; they have been chosen based on their potential significance.
It is not advised to take this medication with any of the following medications. Your doctor may adjust some of the other medications you take or decide not to treat you with this drug.
Desmopressin
Although it is generally not advised, using this medication with any of the following medications may be necessary in some circumstances. Your doctor may alter the dosage or frequency of use of one or both medications if they are prescribed together.
- Bemiparin
- Lutetium Lu 177 Dotatate
- Macimorelin
- Nadroparin
- Ritonavir
- Sargramostim
The best course of action for you might be to combine this medication with any of the following medications, while doing so may increase the chance of some side effects. Your doctor may alter the dosage or frequency of use of one or both medications if they are prescribed together.
- Auranofin
- Ketoconazole
Further Information
Never share your medications with others, keep this and all other medications out of children’s reach, and only take this drug as directed.
To make sure the information on this page pertains to your specific situation, always speak with your healthcare professional.
